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The latest posts from Rubicon Science

These posts are created to provide the reader with the latest news and information on liquid chromatography, liquid handling and osmometry. If you would like further information after reading a post please contact us on

Peter Simpson, Director of Rubicon Science

How pure is the Honey on your bread?

The differences in the ratios of the four common sugars in honey, namely fructose, glucose, sucrose and maltose can help indicate whether a “honey” sample is truly honey or a substitute. Knauer has shown in

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Piperine & its purification from peppercorns

This Application Note from Knauer looks at a preparative method for isolating the alkaloid piperine, using the compact Azura Process HPLC. The piperine product is then analysed using two column types to compare their performance

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Purity Analysis of mRNA using CIMac PrimaS™

CIMac PrimaS™ is a new monolith column range of high performance chromatography products for analysis and purification of mRNA. The positive charge of CIMac PrimaS gives it some anion exchange behavior but hydrogen bonding makes

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HPLC Separation of Additives in Cosmetics

This Application Note shows the separation of twelve common cosmetics additives using HPLC and reverse phase chromatography. The additives separated were Benzyl nicotinate, Butyl p-hydroxybenzoate, 2,6-Di-tert.-butyl-4-methylphenol, 4-Isopropyl-3-methylphenol, Methyl p-hydroxybenzoate, Monoammonium glycyrrhizinate, Pantothenyl ethyl ether, Pyridoxine

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