Menu Close

Detectors

Home > Products > Detectors

Our large portfolio of HPLC and FPLC detectors allow for the analysis of nearly every compound. There are detectors for micro scale up to process scale, with a flexibility that includes a wide range of flow cells, and fibre optics and nebulizer options.

Detectors Heading

AZURA UV/VIS Detectors from Knauer

We are able to offer a choice of UV/VIS detectors, ranging from single variable wavelength to 8-channel diode array detector with LightGuide total reflection technology.

The AZURA UVD 2.1S is a highly competitive single variable wavelength UV detector for HPLC. It offers excellent technical specifications for routine laboratory work. With its small footprint, it is one of the smallest detectors for HPLC on the market. The UVD 2.1S comes in the novel small AZURA housing. The installed deuterium lamp covers a wavelength range from 190 to 500 nm. The UV detector can be controlled with OpenLab EZChrom Edition®, ChromGate®, PurityChrom Bio and ClarityChrom® software, as well as from the front panel (stand-alone operation), via LAN, via RS-232, or through analog input/output; allowing it to be integrated into almost any LC system. Due to a smart design, the flow cell is easily accessible and can be changed very quickly. You can choose between a wide range of flow cells for analytical or preparative LC applications with flow rates from 10 μl/min up to 10 l/min. Also available as a module for the new AZURA ASM 2.2L.

AZURA UV Detector UVD 2.1S

AZURA UV Detector UVD 2.1S
AZURA UV Detector UVD 2.1S
  • Detector type : Variable single wavelength UV detector
  • Operation Area : Analytical HPLC, Preparative HPLC, FPLC
  • Detection channels : 1
    Wavelength range : 190 – 500 nm
  • Linearity : > 2.0 AU at 270 nm (ASTM E1657-98)

The AZURA UV/VIS Detector UVD 2.1L is a competitively priced HPLC spectrophotometer for routine HPLC applications including fast LC methods. Besides offering excellent technical specifications, this robust detector features a highly flexible and compact design. The UVD 2.1L comes with an installed deuterium lamp which covers a wavelength range from 190 to 750 nm. This detector can be controlled with OpenLab® EZChrom, ChromGate®, and ClarityChrom® software, as well as with the Mobile Control software (stand-alone operation), via LAN or through analog input/output; allowing it to be integrated into almost any LC system. Due to a smart design the flow cell is easily accessible and can be changed very quickly. You can choose between a wide range of flow cells for analytical or preparative LC applications with flow rates from 10 μl/min up to 10 l/min.

AZURA UV/VIS Detector UVD 2.1L

AZURA UV/VIS Detector UVD2.1L
AZURA UV/VIS Detector UVD2.1L
  • Detector type : Variable single wavelength UV detector
  • Operation Area : Analytical HPLC, Preparative HPLC
  • Detection channels : 1 Wavelength range : 190 – 750 nm
  • Linearity : > 2.0 AU at 270 nm (ASTM E1657-98)

Variable Multiwavelength Detector

The AZURA MWD 2.1L is an 8 channel, sensitive multiwavelength detector combining high performance with easy handling at an affordable price. A wide range of easily exchangeable cartridge flow cells make this device the right choice for fast, standard analytical, semi-preparative and preparative separations with bio-inert or stainless steel wetted parts. State-of-the-art total reflection flow cells (LightGuide technology) are available for this device providing maximum light throughput (due to total internal reflection) with minimal peak dispersion (due to the small cell volume) to guarantee an optimized S/N ratio. An optional fiber optics adapter offers the possibility to separate the flow cell spatially from the device and thus provides enhanced security for hazardous, explosive or toxic work processes, as well as protecting the device from leakages at high flow rates. The newly developed optical unit and intelligent temperature management ensure for maximum sensitivity combined with minimal baseline drift. Furthermore, easy frontal access and improved safety features enable effortless lamp replacement. This eases maintenance and guarantees short downtimes. This device is also easily upgradable to a diode array detector. The MWD 2.1L comes installed with a deuterium lamp which covers a wavelength range from 190 to 700 nm. This detector can be controlled with OpenLab® EZChrom, ClarityChrom®, Chromeleon® and PurityChrom® software, as well as from the Mobile Control software (stand-alone operation), via LAN or through analog input/output, allowing it to be integrated into almost any LC system.

AZURA UV/VIS Detector MWD 2.1L

AZURA Detector MWD 2.1L
AZURA Detector MWD 2.1L
  • Detector type : Variable multiwavelength detector
  • Operation Area : Analytical HPLC, Preparative HPLC, Analytical UHPLC, FPLC
  • Detection channels : 8 (Digital)/4 (Analog)
  • Wavelength range : 190 – 700 nm
  • Linearity : > 2.0 AU at 274 nm

Diode Array Detectors

The AZURA DAD 2.1L is a highly competitive diode array detector which combines high performance with easy handling at an affordable price. A wide range of easily exchangeable cartridge flow cells make this device the right choice for fast, standard analytical, semi-preparative and preparative separations with bio-inert or stainless steel wetted parts. State-of-the-art total reflection flow cells (LightGuide technology) are available for this device providing maximum light throughput (due to total internal reflection) with minimal peak dispersion (due to the small cell volume) to guarantee an optimized S/N ratio. An optional fiber optics adapter offers the possibility to separate the flow cell spatially from the device and thus provides enhanced security for hazardous, explosive or toxic work processes, as well as protecting the device from leakages at high flow rates. The newly developed optical unit and intelligent temperature management ensure for maximum sensitivity combined with minimal baseline drift. Furthermore, easy frontal access and improved safety features enable effortless lamp replacement. This eases maintenance and guarantees short downtimes. The DAD 2.1L comes installed with a deuterium lamp which covers a wavelength range from 190 to 700 nm. This detector can be controlled with OpenLab® EZChrom, ClarityChrom®, Chromeleon® and PurityChrom® software, as well as with the Mobile Control software (stand-alone operation), via LAN or through analog input/output, allowing it to be integrated into almost any LC system.

AZURA Detector DAD 2.1L

AZURA UV/VIS Detector DAD 2.1L
AZURA UV/VIS Detector DAD 2.1L
  • Detector type : Diode array detector
  • Operation Area : Analytical HPLC, Preparative HPLC, Analytical UHPLC, FPLC
  • Detection channels : 8 (Digital)/4 (Analog)
  • Wavelength range : 190 – 700 nm
  • Number of diodes : 256
  • Linearity : > 2.0 AU at 274 nm

The AZURA DAD 6.1L is a high-end diode array detector with a wavelength range from 190 to 1000 nm. The large selection of flow cells makes it the ideal choice for all liquid chromatography and process applications. It combines excellent performance with easy handling. The AZURA DAD 6.1L is the right choice with its optional fiber optic adapter and the flexibility related to this feature. Especially for applications that require high flow rates or special safety precautions, this adapter and the physical separation from the flow cell means safety. Due to the innovative optical unit with the KNAUER polka-dot technology, the detector offers maximum sensitivity. This makes it ideal for trace analysis. The intelligent temperature management enables fast operational readiness after startup. It also minimizes baseline drift. Due to the frontally accessible deuterium and halogen lamp, the device is easy to service. The downtime is thereby reduced to a minimum if a lamp replacement is necessary. For analytical applications, the AZURA DAD 6.1L is controlled by software packages OpenLab® EZChrom Edition, ClarityChrom®, and Chromeleon®. The PurityChrom® software is also available in the field of purification. The control in the process environment can be implemented via a spring strip, analog outputs, and the Mobile Control.

AZURA Detector DAD 6.1L

AZURA UV/VIS Detector DAD 6.1L
AZURA UV/VIS Detector DAD 6.1L
  • Detector type : Diode array detector
  • Operation Area : Analytical HPLC, Preparative HPLC, Analytical UHPLC, FPLC
  • Detection channels : 8 (Digital)/4 (Analog)
  • Wavelength range : 190 – 1000 nm
  • Number of diodes : 1024
  • Linearity : > 2.5 AU at 274 nm

BlueShadow UV/VIS Stand-Alone Detectors from Knauer

BlueShadow UV/VIS Detector 40D

The BlueShadow detector 40D is a competitively priced HPLC spectrophotometer for routine HPLC applications including fast LC methods. Besides offering excellent technical specifications, this robust detector features a highly flexible and compact design. The BlueShadow Detector 40D comes with an installed deuterium lamp which covers a wavelength range from 190 to 750 nm. This detector can be controlled with ClarityChrom® software, as well as from the touchscreen (stand-alone operation), via LAN, via RS-232, or through analog input/output. Due to a smart design the flow cell is easily accessible and can be changed very quickly. You can choose between a wide range of flow cells for analytical or preparative LC applications with flow rates from 10 μl/min up to 10 l/min.

BlueShadow UV/VIS Detector 40D

BlueShadow UV/VIS Detector 40D
BlueShadow UV/VIS Detector 40D
  • Detector type : Variable single wavelength UV detector
  • Operation Area : Analytical HPLC, Preparative HPLC, FPLC
  • Detection channels : 1
  • Wavelength range : 190 – 750 nm
  • Linearity : > 2.0 AU at 270 nm (ASTM E1657-98)

BlueShadow UV/VIS Detector 50D

The BlueShadow 50D offers high sensitivity and baseline stability for HPLC applications including fast LC methods. With its high speed scanning design, up to four different wavelengths can be monitored simultaneously while acquiring spectral data from 190 to 750 nm. Its remarkable values for noise, drift, and linearity are achieved through smart optical bench technology and the use of optimized components. The detector comes with an installed deuterium lamp which covers a wavelength range from 190 to 750 nm. This detector can be controlled with OpenLab® EZChrom Edition, ClarityChrom® software, as well as via the integrated display (stand-alone operation), via LAN, via RS-232, or through analog input/output. Due to a smart design the flow cell is easily accessible and can be changed very quickly. A wide range of flow cells is available for practically any LC application, including micro flow cells for flow rates up to 10 μl/min and flow cells for preparative HPLC up to 10 l/min.

BlueShadow UV/VIS Detector 50D

BlueShadow UV/VIS Detector 50D
BlueShadow UV/VIS Detector 50D
  • Detector type : Variable single wavelength UV detector
  • Operation Area : Analytical HPLC, Preparative HPLC, FPLC
  • Detection channels : 4
  • Wavelength range : 190 – 750 nm
  • Linearity : > 2.8 AU at 270 nm (ASTM E1657-98)

Conventional UV Detector Flow Cells

The flow cell is an important part for any detector. KNAUER offers a wide variety of flow cells for almost every task from nano-LC for (U)HPLC to preparative HPLC.

UV Detector Flow Cells with Fibre Optics

KNAUER fibre optic technology offers the possibility to separate the flow cell spatially from the detector via fibre optic cables in a distance up to 10 meters. This enables the measurement of UV/ VIS absorption in flow-through mode remotely from the detector. Fibre optics also enable the flow cell to be located very close to the column, minimizing peak broadening.

Analytical Flow Cell for Fibre Optics
3 mm path length & heat resistant
Nano UV Flow Cell
3 mm path length & maximum flow rate 1 µl/min
Preparative UV Flow Cell with Fibre Optics
Path length 0.5 / 1.25 / 2 mm, max flow rate > 10000 ml/min

AZURA Refractive Index Detectors from Knauer

AZURA Refractive Index Detector RID 2.1L

The AZURA RID 2.1L is a sensitive and competitively priced differential refractometer. It is suitable for detecting compounds with little or no UV activity such as alcohols, sugars, lipids or polymers. This instrument is designed for use in analytical HPLC (high performance liquid chromatography) as well as under certain conditions for GPC (gel permeation chromatography) applications. The intelligently designed optical unit with advanced temperature control ensures high sensitivity, fast baseline stabilization, and excellent reproducibility. Furthermore, the long-life LED, highly pressure resistant flow cell, improved safety features and enhanced diagnostics functions guarantee easy handling and minimal maintenance. The wide linear dynamic range, its low internal volume of 43 µl from the inlet to the flow cell and 10 ml/min maximum flow rate make the AZURA RID 2.1L the perfect choice for most laboratory tasks. This detector can be controlled with OpenLAB® EZChrom, ClarityChrom®, Chromeleon® and PurityChrom® Bio software, as well as from the AZURA Mobile Control app (stand-alone operation), via LAN or through analog input/output, allowing it to be integrated into almost any LC system.

AZURA Refractive Index Detector RID 2.1L
AZURA Refractive Index Detector RID 2.1L

AZURA Refractive Index Detector RID 2.1L

  • Detector type : Refractive index detector
  • Operation Area : Analytical HPLC
  • Detection channels : 1
  • Linearity : > 1000 µRIU

AZURA Refractive Index Detector RID 2.1L HighFlow

The AZURA RID 2.1L HighFlow is a sensitive and competitively priced differential refractometer. It is suitable for detecting compounds with little or no UV activity such as alcohols, sugars, lipids or polymers in high concentrations. This instrument is designed for use in semi-preparative and preparative HPLC (high performance liquid chromatography) as well as under certain conditions for GPC (gel permeation chromatography) applications. The intelligently designed optical unit with advanced temperature control ensures high sensitivity, fast baseline stabilization, and excellent reproducibility. Furthermore, the long-life LED, highly pressure resistant flow cell, improved safety features and enhanced diagnostics functions guarantee easy handling and minimal maintenance. The wide linear dynamic range and 100 ml/min maximum flow rate make the AZURA RID 2.1L HighFlow the perfect choice for most laboratory tasks. This detector can be controlled with OpenLAB® EZChrom, ClarityChrom® and PurityChrom® Bio software, as well as from the AZURA Mobile Control app (stand-alone operation), via LAN or through analog input/output, allowing it to be integrated into almost any LC system.

AZURA Refractive Index Detector RID 2.1L HighFlow
AZURA Refractive Index Detector RID 2.1L HighFlow

AZURA Refractive Index Detector RID 2.1L HighFlow

  • Detector type : Refractive index detector
  • Operation Area : Preparative HPLC
  • Detection channels : 1
  • Linearity : > 4000 µRIU

AZURA Conductivity Monitors

Conductivity monitor with flow cell for up to 10 ml/min and optional pH measurement

The AZURA CM 2.1S is a reliable conductivity monitor which is utilized in FPLC to follow salt gradients. Optionally pH values can be measured. Wetted parts are completely biocompatible. The contactless measurements of conductivity reduces the risk of carryover to a minimum. The flow cell covers a flow rate up to 10 ml/min and is delivered with the CM 2.1S.

AZURA Conductivity Monitor CM 2.1S
AZURA Conductivity Monitor CM 2.1S

AZURA Lab-Scale Conductivity Monitor CM 2.1S

  • Detector type : Conductivity monitor
  • Operation Area : HPLC, FPLC
  • Measurement range: 0.1 – 999 mS/cm
  • pH measurement: 2-12
  • Max. flow rate: 10 ml/min
  • Flow cell volume: 30 µl

Conductivity monitor with flow cell for up to 100 ml/min and optional pH measurement

The AZURA CM 2.1S – Prep Scale is a reliable conductivity monitor which is utilized in FPLC to follow salt gradients. Optionally pH values can be measured. Wetted parts are completely biocompatible. The contactless measurements of conductivity reduces the risk of carryover to a minimum. The flow cell covers a flow rate up to 100 ml/min and is delivered with the CM 2.1S.

AZURA Conductivity Monitor CM 2.1S - Prep Scale
AZURA Conductivity Monitor CM 2.1S - Prep Scale

AZURA Lab-Scale Conductivity Monitor CM 2.1S

  • Detector type : Conductivity monitor
  • Operation Area : Preparative HPLC, FPLC
  • Measurement range: 0.1 – 999 mS/cm
  • pH measurement: 2-12
  • Max. flow rate: 100 ml/min
  • Flow cell volume: 300 µl

Chip-based Miniaturized Mass Spectrometer for Preparative HPLC

The 4000 MiD is a miniaturized chip-based single quadrupole mass spectrometer suitable for a broad range of applications. An integrated oil-free pump system enables a small footprint and thereby the installation of this detector nearly everywhere.

The easy to use concept with plug and play consumable results in low maintenance costs and a completely tool-less front end. Due to its small design, the nitrogen consumption of the 4000 MiD is reduced leading to low operating costs. With the MiDas automated sampling unit, the 4000 MiD is the ideal addition for preparative HPLC systems and mass-directed purification.

Miniaturized Mass Spectrometer 4000 MiD
Miniaturized Mass Spectrometer 4000 MiD
  • MS type – Single Quadrapole
  • Ionization modes – ESI (positive & negative)
  • Mass range – 50 m/z to 800 m/z
  • Mass reslution – m/z 0.7 (FWHM)
  • Mass accuracy – m/z ± 0.3 (full scan)
  • Gas requirements – Nitrogen

Fluorescence Detectors

Fluorescence detector RF-20A

The fluorescence detector RF-20A provides world-class sensitivity, excellent maintainability and diverse validation / support functions. It supports a wide range of applications in the wavelength range of 200 to 650 nm from conventional analysis to high-performance analysis. With a signal-to-noise ratio of 1200 for the water-Raman band, the fluorescence detector is well suited for trace analysis. The xenon lamp and flow cell are directly accessible on the device, thus allowing a quick and easy handling and maintenance of the device by the user, thereby minimizing downtime. The lamp life is 2000 hours. When replacing the xenon lamp, no adjustment is required.

Flourescence Detector RF-20A
Flourescence Detector RF-20A

Fluorescence Detector RF-20 A

  • Detector type : Fluorescence detector
  • Operation Area : Analytical HPLC, Analytical UHPLC, FPLC
  • Detection channels : 1
  • Wavelength range : 200 – 650 nm

Fluorescence detector RF-20A

The fluorescence detector RF-20Axs provides world-class sensitivity, excellent maintainability and diverse validation / support functions. It supports a wide range of applications in the wavelength range of 200 to 750 nm from conventional analysis to high-performance analysis.With a signal-to-noise ratio of 2000 for the water-Raman band, the fluorescence detector is very well suited for trace analysis. Measuring cell tempering ensures the lowest possible noise and drift values.

Flourescence Detector RF-20Axs

High End Fluorescence Detector RF-20 Axs

  • Detector type : Fluorescence detector
  • Operation Area : Analytical HPLC, Analytical UHPLC, FPLC
  • Detection channels : 2
  • Wavelength range : 200 – 750 nm

Electrochemical Detector AZURA ECD 2.1

High Sensitive Electrochemical Detector for Liquid Chromatography single cell control, with DC, pulse and scan mode.

AZURA Electrochemical Detector

With its measurement frequency up to 100 Hz, this electrochemical detector is specially designed for super-fast highly sensitive and selective measurement of oxidisable and reducible substances in (U)HPLC. The AZURA ECD 2.1 comprises of a thermostat-controlled Faraday’s cage, accommodating column and flow cell. The AZURA ECD 2.1 unites the three operating modes DC, Pulse and Scan in one instrument. The DC mode covers about 90% of all applications. The pulse mode is important for PAD (Pulsed Amperometric Detection) of e.g. carbohydrates. The scan mode is used to obtain a voltammogram in method optimization. A digital low-pass filter provides an excellent signal-to-noise ratio. For highest sensitivity, the SenCell flow cell is recommended. The correct flow cell can be chosen from a broad variety of flow cells after our advice.