Menu Close

Columns & Media

Home > Products > Columns & Media

Rubicon Science can offer a wide range of columns for both HPLC and FPLC, from analytical to process scale. We supply HPLC and FPLC columns from Knauer, monolith columns from BIA Separations, and Radial columns from Proxcys Downstream Systems.

Liquid Chromatography Columns from KNAUER

Knauer HPLC Columns

KNAUER is able to offer about 6,000 columns for analytical UHPLC and HPLC, as well as for purification tasks with FPLC and preparative scale HPLC.

Still can't find the column you want?

If you are still having problems finding what you are looking for?  Then try out the Knauer Column Finder

Knauer Column Finder
Knauer Column Finder

KNAUER FPLC columns based on Agarose and Dextran.

Sepapure FPLC Columns
Sepapure FPLC Columns

Prepacked 1 and 5 ml FPLC columns and resins for all common protein purification applications:

  • Size Exclusion Chromatography (SEC)
    • Desalting
  • Affinity Chromatography (AC), including:
    • Protein A, Protein G, Glutathione (GST-tag), NiNTA (His-tag).
  • Ion Exchange Chromatography (IEX), including:
    • Q, SP, CM, DEAE.

There are 20 column types available and all are made in Germany.

CLICK HERE for details on the full range

Liquid Chromatography Monolith Columns from BIA Separations

BIA Separations Logo

CIMmultus™ Range for Preparative Applications

CIMmultus Column Range
CIMmultus Column Range

CIMmultus™ preparative column range is the new and improved line of pre-packed chromatographic monolithic columns distinguished by large flow-through channels, designed for working with large proteins (IgG, IgM, PEGylated proteins), viruses (AAV, adenovirus, lentivirus, influenza, bacteriophages), VLPs and pDNA. Due to their performance properties, CIMmultus™ columns can be used as single-use disposable or multi-use columns.

CIMac™ Range for Analytical Applications

CIMac Analytical Columns
CIMac Analytical Columns

CIMac™ Analytical Columns combine all elaborate characteristics of CIM monoliths at analytical scale and are your perfect tool for analysis and control of manufacturing processes, ideal for process analytical technology (PAT). Designed for fast and reproducible HPLC monitoring and quantitation of proteins, viruses, pDNA, and other large biomolecules, they allow you to achieve rapid, high-resolution separations in a matter of minutes. The list below shows all the chemistries available.

CIMmic™ Range for Immobilization

CIMmic Immobilization Columns
CIMmic Immobilization Columns

CIMmic™ is cost-efficient line of small monolithic columns with pre-activated surface used as a basis for preparation of custom-made chromatographic columns, diagnostic tools as well as enzyme reactors by a covalent coupling of numerous ligands, such as proteins, nucleic acids, peptides etc. The covalent nature of the bond between the ligand and matrix reduces leaching and improves stability and reusability.

Monolith Product Packs

Radial Columns from Proxcys Downstream Biosystems

Proxcys Logo

Proxcys Small Scale Columns

The small scale product range starts with a bed volume of 2,5ml and is used for first feasibility studies, resin performance studies, as well as for process optimization. These small scale columns aren’t full radial columns, but are simply a “piece of the full cake” and do offer similar hydrodynamics, identical ratio and identical relative dimensions. Contact Us for more details

Micro RFC Columns
Micro RFC Columns

Micro RFC Columns

A radial column as an axial column with a tapered bore. The ratio between the inlet and outlet is equal to the mean ratio found in all Proxcys Radial columns and is 2:1. Contact Us for more details.

Mini Columns
Mini Columns

Mini Columns

Mini Columns are used to closely mimic full scale radial processes with smaller bed volumes. Flow distribution, bed heights and other physical parameters can be equal to both small scale and full radial process columns. Contact Us for more details.

MP Mini Process Columns
MP Mini Process Columns

MP Mini Process Columns

Mini Process columns are developed and designed to do method development on larger scale of operation and with larger bed heights. Contact Us for more details.

HP-RFC lab line

Full radial columns with short bed height and bed volume between 100ml – 2000ml.

Ideally suited for small scale demanding experiments and Rapid processing of precious products. Contact Us for more details.

Proxcys Process Columns

Proxcys Process Columns
Proxcys Process Columns

Proxcys Process Columns

Proxcys Process columns are used in production all over the world. Thanks to the compactness the columns remain mobile, even a column with a 600L bed volume can be rolled out of the cleanroom, enabling flexible cleanroom-use.

Contact Us for more details.

Pre-packed & pre-validated SUPR columns

SUPR Columns
SUPR Columns

SUPR columns (Single Use Pre-Packed Radial columns)

  • Available in custom sizes between lab volumes of 100 ml and process size of 375 litre column volume!
  • Full cGMP compliant pilot or process columns for fast processing in a plug-and-play mode.
  • Pre-packed and Pre-validated columns can be used for extended periods in campaigns or dedicated projects.
  • Design optimized to reduce manufacturing cost.
  • The unique cartridge design offers the perfect balance between Sustainability and Disposable by offering minimal waste format.
  • Materials of manufacturing POM, EPDM USP class VI approved.

Contact Us for more details.

Proxcys HP-RFC Industrial line

HP-RFC Industrial line
HP-RFC Industrial line

​Compact HP-RFC Tripod Industrial Columns & Systems.

Reduction of bed height reduces operating pressure and boosts productivity. The added advantage is the even smaller footprint and weight.
The HP-RFC Tripod column are available with a bed volume of 150 to 1200 liter and a bed height of 12cm to 30cm. The 230L 12cm model fits nicely between a skid and a 2000 L disposable bag buffer tank, leaving plenty room to move in the cleanroom.

Contact Us for more details.

KYA Technologies HPLC Columns

KYA Technology Logo

KYA Technologies HiQ sil™ columns 

The HiQ sil™ columns are made from an ultra pure silica gel as the starting material. The unique manufacturing process ensures high mechanical strength and this gives a long life under the toughest conditions. The HiQ sil gel is manufactured in a range of particle sizes, pore sizes and with a variety of chemical surface bondings for reverse phase and normal phase chromatography. Contact Us for more details.